| Customization: | Available |
|---|---|
| Application: | Pharmaceutical Industry |
| Disposable: | No |
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The Pump Bioreactor System is an advanced biological manufacturing device mainly used in the fields of biopharmaceuticals, tissue engineering, microbial fermentation, and other life sciences research. The system achieves precise control and optimization of the biological culture process by integrating pumping equipment, bioreactor containers (bioreactors), sensors, controllers, and data acquisition and analysis units.
Key components and functions: 1 Pump: It is one of the core components of the system, responsible for the transportation of materials, including the input of culture medium, the addition of nutrients, the discharge of products, and the supply of gases (such as oxygen). There are various types of pumps, such as peristaltic pumps, centrifugal pumps, etc., which are selected according to specific needs to ensure precise control of fluid transmission and sterile operation.
2. Bioreactor: As a place for cell or microbial growth, the design must meet specific biocompatibility, stirring efficiency, and mass and heat transfer requirements. The reactor can be equipped with agitators, ventilation devices, etc. to maintain an appropriate level of dissolved oxygen PH value, temperature, and shear force promote cell proliferation or product synthesis.
3. Control system: including sensors (such as pH sensors, dissolved oxygen electrodes, temperature probes) and automatic controllers, real-time monitoring of biological reaction conditions, and automatic adjustment of pump speed, gas flow rate, heating/cooling, etc. according to preset parameters to maintain the optimal cultivation environment.
4. Data management software: Collect and analyze data from bioreactors, enabling researchers to remotely monitor reaction processes, optimize cultivation strategies, and improve production efficiency and product quality. Application advantages: • Precise control: Through precise regulation of the pump, precise supply of nutrients and effective elimination of metabolites are achieved, improving the efficiency of biological reactions and product yield Automation: reduces manual intervention, reduces pollution risks, and improves the continuity and stability of experiments or production Flexibility: The system configuration can be adjusted according to different research or production needs, suitable for various biological processes Data tracking and analysis: Easy to record and analyze biological reaction processes, helpful for process optimization and quality control.
In summary, the pump bioreactor system is a key equipment for achieving efficient and controllable biological manufacturing in the field of modern biotechnology.
Nominal volume: 10L,15L ,30L,50L,70L,100L,150L,200L
Liquid loading coefficient: ≥70%
Tank configuration :
Stainless steel SUS316/SUS304;
Jacket temperature control,optimized diversion design;
Interior surface polishing ,Ra≤0.6μm; exterior surface polishing or matte treatment;
Wide visual angle long-bar sight glass, PH electrode ,DO electrode, temperature electrode with complete connections;
The tank cover is equipped with the flame inoculation port and standby feeding port.
Stirring system
Top mechanical stirring system , aseptic mechanical seal system , DC stirring motor or AC motor;
Standard configuration 2-layer flat vane , first-class high-efficiency defoaming vane , bending vane and axial flow vane are optional;
Speed control available , digital setting of rotation speed control.
Structure mode
Floor type framework , space saving , convenient operation.
Ventilating system
Deep ventilating ,full stainless steel pipe;
Liquid deep ventilating;
Glass rotor flow-meter display , pressure gauge display , manual valve flow adjustment;
Equipped with German Sartorius high-efficiency bacteria removing filter of stainless shell with a precision of 0.01μm;
External compressed air is required , equipped with high quality water removing pressure stabilizer for continuous and stable air supply;
The mass flow controller is optional to automatically control air flow.
Tank pressure control
The top exhaust port is equipped with the pointer pressure gauge to display the tank pressure. The stainless steel valve adopts manual control.
The optional imported pressure transmitter and automatic control valve realize automatic control of tank pressure
Temperature control
Online inspection , digital setting , free switching between automatic and manual control;
Pt-100 temperature probe;
Electric heating temperature control and external cooling water for automatic temperature control.
PH control
Online inspection , 2-way peristaltic pump automatic incremental feeding of acid or alkali solution for adjustment;
Imported PH electrode realizes high temperature steam disinfection.
Dissolved oxygen(DO)
Online inspection , with a range of 0-100% or 0-200%;
Imported DO electrode realizes high temperature steam disinfection;
Optional , linked control with rotation speed and ventilation.
Feeding control
Standard configuration 1-way peristaltic pump time proportional incremental feeding , with the volume of incremental feeding being displayed and recorded.
Defoaming mode
Conducting type foam electrode , automatic alarming in case of abnormal foam situation;
Standard configuration 1-way peristaltic pump automatic/manual incremental feeding of defoaming agent , with the volume of incremental feeding being displayed and recorded.
Control system
Siemens PLC controller true color touch screen with complete functions and stable running .
Sterilizing mode
SIP , manual control
Equipment features
SIP , safety and reliable ;
Without driving leakage risk;
Wide visual angle vertical sight glass with clear observation;
Various reliable inoculation modes (standard configuration flame inoculation port,differential pressure inoculation port and other various optional forma);
Floor type tank with beautiful appearance;
Easy operation , assembly and disassembly;
Products of special specifications can be made to order;
Optional
1.Multi-way feeding
2.Automatic sterilization
3.Weighing of fed materials
4.Tank body weighing
5.Rich oxygen bypass
6.ORP online inspection
7.Air flow automatic inspection and control
8.Tail gas O2,CO2 content online inspection
9.Methanol (alcohol) content online inspection
| Coefficient of charge | Ventilation ratio | Height-diameter ratio | Culture types |
| 70~75% | 1~2vvm | 2~2.5 | fungus,bacterium,actinomyces. |
Pre sales services
After-sale service
1. Equipment warranty period: We provide a one-year free warranty service for mechanical equipment. If any non-human caused problems occur during the warranty period, we will provide free repair or replacement services.
2. Maintenance and upkeep services: We provide regular or irregular equipment maintenance and upkeep services to ensure the normal operation of the equipment. We will provide 24-hour online technical support services.
3. Accessory supply: We guarantee to provide original factory accessories in a timely manner in case of equipment damage or replacement of parts.
4. Training services: In order to enable customers to effectively operate and maintain equipment, we will provide equipment operation and maintenance training.
5. Installation and debugging: We will provide equipment installation and debugging services to ensure that the equipment is installed correctly and can operate normally.
1 ) Q: How can we visit your factory?
A: If you come from abroad, air to shanghai airport, then we can pick you up at airport.
2) Q: How do you ensure the quality of your products?
A: Our Company is a state owned enterprise with more than 16 years experience , strict operation policy is performed, advanced processing machines guarangtee the precision of all components, workers with operation license, parts get multiprocessing, transmission& electrical parts are of international famous brand. Series of test and inspection are done in the whole producing state.
3) Q: What payment methods your company accept?
A: We accept most of the payment methods , but mainly accept T/T, L/C at sight .
4) Q: How long is the warranty time for your products?
A: Our officially promised warranty time is 12 months after commissioning .
5) Q: I am new in this field,can you supply us turnkey services?
A: YES.We can supply all the system including Market Analysis/Product Analysis/Location Choice/Processing Flow Design/Equipment Layout Design/Building Design direction/Equipment mode selection/Equipment Manufacturing/Equipment Mounting/Equipment Debugging/Worker Training.
6) Q: What ' s the shipment terms and delivery time of your company?
A: Well, the delivery time depend on the quantity of your order. Usually is 20 days . For some customized machine 30 days is necessary.
7) Q: Can you supply OEM services?
A: Yes,we have our R&D team,and we have more than 400 workers with workshop area 75000 square meters.
8) Q: Do you give any Discount?
A: I will surely try my best to help you get those by the best price and good service at the same time.
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